I have seen it only once on a fictional crime show.
Has there ever been a real-life criminal with chimerism who took advantage of their condition when committing crimes?
The only way to use it would be to leave behind the "wrong" DNA.
It would be virtually impossible. The criminal would have to wear a "clean suit" and have a sample of the "wrong" DNA to leave ... Then make sure they NEVER left that DNA anywhere in their daily life.